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Enlarged Spleen (Splenomegaly) Symptoms and Causes

Associated Signs & Symptoms

Splenomegaly is a sign of an underlying disease, not a health condition in itself. While it may be the only symptom of an illness, it often occurs in conjunction with other signs and symptoms. These can include an enlarged liver, abdominal pain or tenderness, anemia, easy bruising, fatigue, weight loss, and fever. In some cases, additional signs and symptoms of the underlying cause of splenomegaly may also be present. It is important to see a doctor if splenomegaly is suspected, as the underlying cause must be identified and treated.

1. Abdominal discomfort

It is often described as a feeling of unease rather than actual pain. It may be felt in the left upper portion of the abdomen, though some individuals may experience a radiating discomfort in their left shoulder. Physical examination may also reveal tenderness in the area.